Fixed combination of hyaluronic acid and dexpanthenol in improving the state of the front surface of the eye after cataract surgery

Authors

  • S.O. Rykov Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine Kyiv City Clinical Ophthalmological Hospital “Eye Microsurgical Center”, Kyiv, Ukraine http://orcid.org/0000-0001-8925-6456
  • L. I. Denysyuk Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine Kyiv City Clinical Ophthalmological Hospital “Eye Microsurgical Center”, Kyiv, Ukraine
  • L.P. Tutchenko Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine Kyiv City Clinical Ophthalmological Hospital “Eye Microsurgical Center”, Kyiv, Ukraine
  • M.G. Lysenko Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine Kyiv City Clinical Ophthalmological Hospital “Eye Microsurgical Center”, Kyiv, Ukraine
  • M.V. Skovron Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine
  • S.I. Kosuba Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine Kyiv City Clinical Ophthalmological Hospital “Eye Microsurgical Center”, Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2309-8147.7.3.2019.179619

Keywords:

dry eye disease, SuperOptic Complete, phacoemulsification, epitheliopathy

Abstract

An analysis of the use of preservative-free eye drops SuperOptic Complete (Polpharma), a fixed combination of hyaluronic acid and dexpanthenol, was performed in 60 patients aged 44 to 82 years with dry eye disease after phacoemulsification. Patients were randomly divided into two comparable groups: I (n = 30, SuperOptic Complete was used 4 times a day for 1 month postoperatively) and II (n = 30, control group). Patients were examined at baseline and 1 month after surgery. The key significant findings (p < 0.05) were as follows. Group I showed improvement of: tear meniscus height, tear breakup time, Schirmer I test, self-assessment of ocular comfort (ten-point analogue scale), ocular surface appearance and staining (Oxford scale) and ocular surface epithelial cells appea­rance (laser scanning confocal microscopy on Heidelberg Retina Tomograph II with Rostock Cornea Module). In group II, tear meniscus height, tear breakup time, self-assessment of ocular comfort and the state of the corneal epithelial cells according to laser scanning confocal microscopy worsened; there were no changes according to the Schirmer I test and Oxford scale. The mentioned achievements evidence the effectiveness of SuperOptic Complete for the treatment of dry eye disease after cataract surgery.

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Published

2021-09-28

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